Optimization of Resource-Constrained Policies for COVID-19 Testing and Quarantining

Konstantin Berestizshevsky, Koffi-Emmanuel Sadzi, Guy Even, Moni Shahar

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10.23919/JCN.2021.000029

Abstract :We address the problem of controlling the COVID19 contagion with a limited number of PCR-tests. We developed a tool that can assist policy makers in decisions as well as in justifying these decisions. Our tool consists of: A stochastic disease model, a compressed representation of interactions between people via a graph that scales well to large populations, policies for selecting PCR-testees per day, and a simulator that simulates the spread of the COVID-19 while taking into account the testing and quarantine decisions of the chosen policy. The graph model includes features that help determine the infection risk of individuals. We consider both external infection (inflicted by people outside the studied community) as well as internal infection. The graph model and known infections induce weights to people. These weights are used to select the testees per day in a greedy algorithm and in a linear-programming optimization algorithm. Our simulations indicate a reduction in total morbidity of 30−50% using the optimization algorithm compared to random sampling. A reduction of up to 40% in peak morbidity is achieved compared to random sampling. We also studied the efficiency of quarantining in various policies. 

Index terms :Disease model, optimization, simulation